Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure.

Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure.

The main structural component of connective tissues is fibrillar, cross-linked collagen whose fibrillogenesis can be modulated by Small Leucine-Rich Proteins/Proteoglycans (SLRPs). Not all SLRPs' effects on collagen and extracellular matrix in vivo have been elucidated; one of the less investig...

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Bibliographic Details
Main Authors: Marco Maccarana, René B Svensson, Anki Knutsson, Antonis Giannopoulos, Mea Pelkonen, MaryAnn Weis, David Eyre, Matthew Warman, Sebastian Kalamajski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184028&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184028&type=printable

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