Lipopolysaccharide (LPS) Inner-Core Phosphates Are Required for Complete LPS Synthesis and Transport to the Outer Membrane in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> PAO1

ABSTRACT Gram-negative outer membrane (OM) integrity is maintained in part by Mg2+ cross-links between phosphates on lipid A and on core sugars of adjacent lipopolysaccharide (LPS) molecules. In contrast to other Gram-negative bacteria, waaP, encoding an inner-core kinase, could not be inactivated i...

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Bibliographic Details
Main Authors: Angela M. DeLucia, David A. Six, Ruth E. Caughlan, Patricia Gee, Ian Hunt, Joseph S. Lam, Charles R. Dean
Format: Article
Language:English
Published: American Society for Microbiology 2011-09-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00142-11