Molecular Details of Retinal Guanylyl Cyclase 1/GCAP-2 Interaction

Molecular Details of Retinal Guanylyl Cyclase 1/GCAP-2 Interaction

The rod outer segment guanylyl cyclase 1 (ROS-GC1) is an essential component of photo-transduction in the retina. In the light-induced signal cascade, membrane-bound ROS-GC1 restores cGMP levels in the dark in a calcium-dependent manner. With decreasing calcium concentration in the intracellular com...

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Bibliographic Details
Main Authors: Anne Rehkamp, Dirk Tänzler, Claudio Iacobucci, Ralph P. Golbik, Christian H. Ihling, Andrea Sinz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cross-linking
guanylyl cyclase-activating protein (GCAP)
interaction site
mass spectrometry
photo-transduction
rod outer segment guanylyl cyclase (ROS-GC1)
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00330/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00330/full

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