Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs

Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs

Abstract Background Gene regulation is critical for proper cellular function. Next-generation sequencing technology has revealed the presence of regulatory networks that regulate gene expression and essential cellular functions. Studies investigating the epigenome have begun to uncover the complex m...

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Bibliographic Details
Main Authors: Collin B. Merrill, Austin B. Montgomery, Miguel A. Pabon, Andrey A. Shabalin, Aylin R. Rodan, Adrian Rothenfluh
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Genomics
Subjects:
Drosophila melanogaster
S2 cells
Insulin
RNA-seq
ATAC-seq
Online Access:https://doi.org/10.1186/s12864-022-08637-y

Internet

https://doi.org/10.1186/s12864-022-08637-y

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