Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons

Abstract High throughput RNA sequencing experiments are widely conducted and analyzed to identify differentially expressed genes (DEGs). The statistical models calculated for this task are often not clear to practitioners, and analyses may not be optimally tailored to the research hypothesis. Often,...

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Bibliographic Details
Main Authors: Julia C. Duda, Carolin Drenda, Hue Kästel, Jörg Rahnenführer, Franziska Kappenberg
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47057-0