Prevalence of glucose 6-phosphate dehydrogenase deficiency in highly malaria-endemic municipalities in the Brazilian Amazon: A region-wide screening study

Prevalence of glucose 6-phosphate dehydrogenase deficiency in highly malaria-endemic municipalities in the Brazilian Amazon: A region-wide screening study

Summary: Background: Difficulties associated with the assessment of glucose-6-phosphate dehydrogenase deficiency (G6PDd), particularly in remote areas, hinders the safe use of 8-aminoquinolines such as primaquine (PQ) and tafenoquine against Plasmodium vivax malaria due to the risk of haemolysis. M...

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Bibliographic Details
Main Authors: Joabi Rocha Nascimento, Jose Diego Brito-Sousa, Anne Cristine Gomes Almeida, Marly M Melo, Monica Regina Farias Costa, Laila Rowena Albuquerque Barbosa, Reinaldo Nery Ramos, Alexandre Vilhena Silva-Neto, Patricia Carvalho da Silva Balieiro, Erick Frota Gomes Figueiredo, Emanuelle Lira Silva, Djane Clarys Baia-da-Silva, Quique Bassat, Gustavo Romero, Gisely Cardoso Melo, Vanderson Souza Sampaio, Marcus Lacerda, Wuelton Monteiro
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:The Lancet Regional Health. Americas
Subjects:
Vivax malaria
Primaquine
G6PD deficiency
Brazilian Amazon
Elimination
Hemolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2667193X22000904

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http://www.sciencedirect.com/science/article/pii/S2667193X22000904

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