Unraveling the potential effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on the Protein structure and function of the human SLC30A8 gene on type 2 diabetes and colorectal cancer: An In silico approach

Unraveling the potential effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on the Protein structure and function of the human SLC30A8 gene on type 2 diabetes and colorectal cancer: An In silico approach

Background and aims: The single nucleotide polymorphisms (SNPs) in SLC30A8 gene have been recognized as contributing to type 2 diabetes (T2D) susceptibility and colorectal cancer. This study aims to predict the structural stability, and functional impacts on variations in non-synonymous SNPs (nsSNPs...

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Bibliographic Details
Main Authors: Md. Moin Uddin, Md. Tanvir Hossain, Md. Arju Hossain, Asif Ahsan, Kamrul Hasan Shamim, Md. Arif Hossen, Md. Shahinur Rahman, Md Habibur Rahman, Kawsar Ahmed, Francis M. Bui, Fahad Ahmed Al-Zahrani
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Heliyon
Subjects:
SLC30A8
T2D
Missense
Non-synonymous
Polymorphism
And colorectal cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024133117

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http://www.sciencedirect.com/science/article/pii/S2405844024133117

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