Transcriptome-Wide Analysis of RNA N6-Methyladenosine Modification in Adriamycin-Resistant Acute Myeloid Leukemia Cells

Transcriptome-Wide Analysis of RNA N6-Methyladenosine Modification in Adriamycin-Resistant Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is one of the most aggressive hematopoietic malignancies. Patients still suffer from refractory/relapsed disease after anthracycline-based therapy, which leads to a poor prognosis. N6-Methyladenosine (m6A) is the most abundant post-transcriptional modification in eukaryo...

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Bibliographic Details
Main Authors:	Shu Fang, Bo Peng, Yanan Wen, Jingjing Yang, Hao Wang, Ziwei Wang, Kun Qian, Yan Wei, Yifan Jiao, Chunji Gao, Liping Dou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Series:	Frontiers in Genetics
Subjects:	acute myeloid leukemia drug resistance N6-methyladenosine gene expression METTL3
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2022.833694/full

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