Metabolic Adaptations in an Endocrine-Related Breast Cancer Mouse Model Unveil Potential Markers of Tumor Response to Hormonal Therapy

Metabolic Adaptations in an Endocrine-Related Breast Cancer Mouse Model Unveil Potential Markers of Tumor Response to Hormonal Therapy

Breast cancer (BC) is the most common type of cancer in women and, in most cases, it is hormone-dependent (HD), thus relying on ovarian hormone activation of intracellular receptors to stimulate tumor growth. Endocrine therapy (ET) aimed at preventing hormone receptor activation is the primary treat...

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Bibliographic Details
Main Authors: Rita Araújo, Victoria Fabris, Caroline A. Lamb, Claudia Lanari, Luisa A. Helguero, Ana M. Gil
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
endocrine-related breast cancer
murine model
metabolomics
metabonomics
therapy resistance
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.786931/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.786931/full

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