Microvascular Sex- and Age- Dependent Phosphodiesterase Expression
Objective: The cyclic nucleotide second messengers, cAMP and cGMP, are pivotal regulators of vascular functions; their cellular levels are tightly controlled by the cyclic nucleotide hydrolases, phosphodiesterases (PDE). Biologic sex and age are recognized as independent factors impacting the mechan...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-07-01
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Series: | Frontiers in Aging |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fragi.2021.719698/full |