Microvascular Sex- and Age- Dependent Phosphodiesterase Expression

Microvascular Sex- and Age- Dependent Phosphodiesterase Expression

Objective: The cyclic nucleotide second messengers, cAMP and cGMP, are pivotal regulators of vascular functions; their cellular levels are tightly controlled by the cyclic nucleotide hydrolases, phosphodiesterases (PDE). Biologic sex and age are recognized as independent factors impacting the mechan...

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Bibliographic Details
Main Authors: Jianjie Wang, Murtaza M. Kazmi, Virginia H. Huxley
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Aging
Subjects:
phosphodiesterase
arterioles
venules
sex
age
adult
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2021.719698/full

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