Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters

Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the bloodstream are associated with a poor prognosis, elevated metastatic potential, higher proliferation rate, and distinct molecular features compared to single CTCs. Studying CTC clusters may give us information on th...

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Bibliographic Details
Main Authors: Celine Macaraniag, Qiyue Luan, Jian Zhou, Ian Papautsky
Format: Article
Language:English
Published: AIP Publishing LLC 2022-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0093806