Recent technological advances in correlative light and electron microscopy for the comprehensive analysis of neural circuits

Light microscopy (LM) covers a relatively wide area and is suitable for observing the entire neuronal network. However, resolution of LM is insufficient to identify synapses and determine whether neighboring neurons are connected via synapses. In contrast, the resolution of electron microscopy (EM)...

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Bibliographic Details
Main Authors: Hirohide Iwasaki, Sotaro Ichinose, Yuki Tajika, Tohru Murakami
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Neuroanatomy
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2022.1061078/full