Validation of a Metagenomic Next-Generation Sequencing Assay for Lower Respiratory Pathogen Detection

Validation of a Metagenomic Next-Generation Sequencing Assay for Lower Respiratory Pathogen Detection

ABSTRACT Lower respiratory infection (LRI) is the most fatal communicable disease, with only a few pathogens identified. Metagenomic next-generation sequencing (mNGS), as an unbiased, hypothesis-free, and culture-independent method, theoretically enables the detection of all pathogens in a single te...

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Bibliographic Details
Main Authors: Zhenli Diao, Huiying Lai, Dongsheng Han, Bin Yang, Rui Zhang, Jinming Li
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
mNGS
validation
metagenomics
respiratory tract infection
pneumonia
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03812-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.03812-22

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