Scorpion Peptide Smp24 Exhibits a Potent Antitumor Effect on Human Lung Cancer Cells by Damaging the Membrane and Cytoskeleton In Vivo and In Vitro

Scorpion Peptide Smp24 Exhibits a Potent Antitumor Effect on Human Lung Cancer Cells by Damaging the Membrane and Cytoskeleton In Vivo and In Vitro

Smp24, a cationic antimicrobial peptide identified from the venom gland of the Egyptian scorpion <i>Scorpio maurus palmatus</i>, shows variable cytotoxicity on various tumor (KG1a, CCRF-CEM and HepG2) and non-tumor (CD34<sup>+</sup>, HRECs, HACAT) cell lines. However, the eff...

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Bibliographic Details
Main Authors: Ruiyin Guo, Junfang Liu, Jinwei Chai, Yahua Gao, Mohamed A. Abdel-Rahman, Xueqing Xu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Toxins
Subjects:
lung cancer
antimicrobial peptide
scorpion
venom
tumor
Online Access:https://www.mdpi.com/2072-6651/14/7/438

Internet

https://www.mdpi.com/2072-6651/14/7/438

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