To Develop With Or Without The Prion Protein

To Develop With Or Without The Prion Protein

The deletion of the cellular form of the prion protein (PrPC) in mouse, goat and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrPC quasi- ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role in neurodegenerat...

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Bibliographic Details
Main Authors: Sophie eHalliez, Bruno ePasset, Séverine eMartin-Lannerée, Julia eHernandez-Rapp, Hubert eLaude, Sophie eMouillet-Richard, Jean-Luc eVilotte, Vincent eBéringue
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Cell Adhesion
Cytoskeleton
Stem Cells
development
prion protein
neural development
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00058/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00058/full

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