Iron-sulfur clusters are involved in post-translational arginylation

Iron-sulfur clusters are involved in post-translational arginylation

The enzyme ATE1 catalyzes eukaryotic post-translation arginylation, a key protein modification necessary for cellular homeostasis. Here, the authors show that ATE1s are previously unrealized iron-sulfur proteins that use this oxygen-sensitive inorganic cofactor to control cellular arginylation

Bibliographic Details
Main Authors: Verna Van, Janae B. Brown, Corin R. O’Shea, Hannah Rosenbach, Ijaz Mohamed, Nna-Emeka Ejimogu, Toan S. Bui, Veronika A. Szalai, Kelly N. Chacón, Ingrid Span, Fangliang Zhang, Aaron T. Smith
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36158-z

Internet

https://doi.org/10.1038/s41467-023-36158-z

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