Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis

Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis

Clinical observations and studies on different animal models of acquired epilepsy consistently demonstrate that blood–brain barrier (BBB) leakage can be an important risk factor for developing recurrent seizures. However, the involved signaling pathways remain largely unclear. Given the important ro...

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Bibliographic Details
Main Authors: D. Isaev, I. Lushnikova, O. Lunko, O. Zapukhliak, O. Maximyuk, A. Romanov, G.G. Skibo, C. Tian, G.L. Holmes, E. Isaeva
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Neurobiology of Disease
Subjects:
Thrombin
Protease-activated receptor
Hippocampus
Pilocarpine
Epileptogenesis
Status epilepticus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115001047

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http://www.sciencedirect.com/science/article/pii/S0969996115001047

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