Integrating bioinformatics and experimental models to investigate the mechanism of the chelidonine-induced mitotic catastrophe via the AKT/FOXO3/FOXM1 axis in breast cancer cells

Integrating bioinformatics and experimental models to investigate the mechanism of the chelidonine-induced mitotic catastrophe via the AKT/FOXO3/FOXM1 axis in breast cancer cells

Breast cancer (BC) is currently the most frequent and lethal cancer among women, and therefore, identification of novel biomarkers and potential anticancer agents for BC is crucial. Chelidonine is one of the main active ingredients of Chelidonium majus, which has been applied in Chinese medicine pre...

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Bibliographic Details
Main Authors: Huimin Li, Xiyu Tang, Zhiwei Sun, Zhongyuan Qu, Xiang Zou
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-11-01
Series:Biomolecules & Biomedicine
Subjects:
Chelidonine
breast cancer (BC)
AKT/FOXO3/FOXM1 axis
cell cycle arrest
mitotic catastrophe
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/9665

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/9665

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