m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2

m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2

Pancreatic cancer (PC) is one of the most fatal cancers with a very poor prognosis. Here, we found that N6-methyladenosine (m6A) RNA demethylase fat mass and obesity-related protein (FTO) promote the growth, migration and invasion of PC. FTO expression level is increased in human PC and is associate...

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Bibliographic Details
Main Authors: Wei Wang, Ying He, Lu-Lu Zhai, Long-Jiang Chen, Li-Chao Yao, Lun Wu, Zhi-Gang Tang, Jin-Zhuo Ning
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
m6a
fto
tfpi-2
pancreatic cancer
progression
Online Access:http://dx.doi.org/10.1080/15592294.2022.2061117

Internet

http://dx.doi.org/10.1080/15592294.2022.2061117

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