Inducible HSP70 Is Critical in Preventing the Aggregation and Enhancing the Processing of PMP22

Chaperones, also called heat shock proteins (HSPs), transiently interact with proteins to aid their folding, trafficking, and degradation, thereby directly influencing the transport of newly synthesized molecules. Induction of chaperones provides a potential therapeutic approach for protein misfoldi...

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Bibliographic Details
Main Authors: Vinita G. Chittoor-Vinod, Sooyeon Lee, Sarah M. Judge, Lucia Notterpek
Format: Article
Language:English
Published: Taylor & Francis 2015-02-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/1759091415569909