On the Role of Glycolysis in Early Tumorigenesis—Permissive and Executioner Effects
Reprogramming energy production from mitochondrial respiration to glycolysis is now considered a hallmark of cancer. When tumors grow beyond a certain size they give rise to changes in their microenvironment (e.g., hypoxia, mechanical stress) that are conducive to the upregulation of glycolysis. Ove...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/12/8/1124 |