Toxic tau: structural origins of tau aggregation in Alzheimer's disease

Toxic tau: structural origins of tau aggregation in Alzheimer's disease

Alzheimer’s disease is characterized by the extracellular accumulation of the amyloid β in the form of amyloid plaques and the intracellular deposition of the microtubule-associated protein tau in the form of neurofibrillary tangles. Most of the Alzheimer’s drugs targeting amyloid β have been failed...

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Bibliographic Details
Main Authors: Abdullah Al Mamun, Md Sahab Uddin, Bijo Mathew, Ghulam Md Ashraf
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; neurofibrillary tangles; shape-shifting nature of tau; tau aggregation; toxic tau
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=8;spage=1417;epage=1420;aulast=Mamun

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=8;spage=1417;epage=1420;aulast=Mamun

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