Human β-Defensin 3 Inhibits <i>Porphyromonas Gingivalis</i> Lipopolysaccharide-Induced Oxidative and Inflammatory Responses of Microglia by Suppression of Cathepsins B and L

Human β-Defensin 3 Inhibits <i>Porphyromonas Gingivalis</i> Lipopolysaccharide-Induced Oxidative and Inflammatory Responses of Microglia by Suppression of Cathepsins B and L

Recently, the effects of antibacterial peptides are suggested to have therapeutic potential in Alzheimer’s disease. Furthermore, systemic treatment of <i>Porphyromonas gingivalis</i> (<i>Pg</i>) lipopolysaccharide (LPS) induced Alzheimer’s disease-like neuropathological chang...

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Bibliographic Details
Main Authors: Erika Inoue, Shiyo Minatozaki, Yui Katsuta, Saori Nonaka, Hiroshi Nakanishi
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
antibacterial peptide
cathepsin B
cathepsin L
human β-defensins
interleukin-6
lipopolysaccharide
Online Access:https://www.mdpi.com/1422-0067/23/23/15099

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https://www.mdpi.com/1422-0067/23/23/15099

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