Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and suggests anti-inflammatory mechanism of action.

Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and suggests anti-inflammatory mechanism of action.

Osteoarthritis (OA) is characterized by cartilage degradation and chronic joint inflammation. Mesenchymal stem cells (MSCs) have shown promising results in OA, but their mechanism of action is not fully understood. We hypothesize that MSCs polarize macrophages, which are strongly associated with joi...

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Bibliographic Details
Main Authors: Amanda M Hamilton, Wing-Yee Cheung, Alejandro Gómez-Aristizábal, Anirudh Sharma, Sayaka Nakamura, Amélie Chaboureau, Shashank Bhatt, Razieh Rabani, Mohit Kapoor, Paula J Foster, Sowmya Viswanathan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214107

Internet

https://doi.org/10.1371/journal.pone.0214107

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