Evaluation of stromal cell infiltration in the tumor microenvironment enable prediction of treatment sensitivity and prognosis in colon cancer

Evaluation of stromal cell infiltration in the tumor microenvironment enable prediction of treatment sensitivity and prognosis in colon cancer

Current clinical factors for screening candidates that might benefit from adjuvant chemotherapy in colon cancer are inadequate. Tumor microenvironment, especially the stromal components, has the potential to determine treatment response. However, clinical translation of the tumor-associated stromal...

Full description

Bibliographic Details
Main Authors: Rui Zhou, Zhaowei Wen, Yifu Liao, Jingjing Wu, Shaoyan Xi, Dongqiang Zeng, Huiying Sun, Jianhua Wu, Min Shi, Jianping Bin, Yulin Liao, Wangjun Liao
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Stromal cell infiltration
Machine learnin
Gene signature
Treatment sensitivity
CRISPR library screen
Colon cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022001544

Internet

http://www.sciencedirect.com/science/article/pii/S2001037022001544

Similar Items