Loss of <i>atm</i> in Zebrafish as a Model of Ataxia–Telangiectasia Syndrome

Ataxia–telangiectasia mutated (<i>ATM</i>) is a key DNA damage signaling kinase that is mutated in humans with ataxia–telangiectasia (A-T) syndrome. This syndrome is characterized by neurodegeneration, immune abnormality, cancer predisposition, and premature aging. To better understand t...

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Bibliographic Details
Main Authors: Kehua Chen, Peng Wang, Jingrun Chen, Yiling Ying, Yi Chen, Eric Gilson, Yiming Lu, Jing Ye
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/2/392