Co-exposure to lipopolysaccharide and desert dust causes exacerbation of ovalbumin-induced allergic lung inflammation in mice via TLR4/MyD88-dependent and -independent pathways

Abstract Background Lipopolysaccharide (LPS) often presents in high concentrations in particulate matter (PM), few studies have reported the enhancing effects of both LPS and PM on airway inflammation in mice and the role of toll-like receptors (TLRs) in this process. Asian sand dust (ASD) is observ...

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Bibliographic Details
Main Authors: Yahao Ren, Takamichi Ichinose, Miao He, Seiichi Youshida, Masataka Nishikawa, Guifan Sun
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Online Access:https://doi.org/10.1186/s13223-019-0396-4