Identification and characterization of whole blood gene expression and splicing quantitative trait loci during early to mid-lactation of dairy cattle

Identification and characterization of whole blood gene expression and splicing quantitative trait loci during early to mid-lactation of dairy cattle

Abstract Background Characterization of regulatory variants (e.g., gene expression quantitative trait loci, eQTL; gene splicing QTL, sQTL) is crucial for biologically interpreting molecular mechanisms underlying loci associated with complex traits. However, regulatory variants in dairy cattle, parti...

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Bibliographic Details
Main Authors: Yongjie Tang, Jinning Zhang, Wenlong Li, Xueqin Liu, Siqian Chen, Siyuan Mi, Jinyan Yang, Jinyan Teng, Lingzhao Fang, Ying Yu
Format: Article
Language:English
Published: BMC 2024-05-01
Series:BMC Genomics
Subjects:
Holstein cows
Early to mid-lactation period
eQTL
sQTL
Colocalization
TWAS
Online Access:https://doi.org/10.1186/s12864-024-10346-7

Internet

https://doi.org/10.1186/s12864-024-10346-7

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