Albuminuria-Related Genetic Biomarkers: Replication and Predictive Evaluation in Individuals with and without Diabetes from the UK Biobank

Albuminuria-Related Genetic Biomarkers: Replication and Predictive Evaluation in Individuals with and without Diabetes from the UK Biobank

Increased albuminuria indicates underlying glomerular pathology and is associated with worse renal disease outcomes, especially in diabetic kidney disease. Many single nucleotide polymorphisms (SNPs), associated with albuminuria, could be potentially useful to construct polygenic risk scores (PRSs)...

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Bibliographic Details
Main Authors: Marisa Cañadas-Garre, Andrew T. Kunzmann, Kerry Anderson, Eoin P. Brennan, Ross Doyle, Christopher C. Patterson, Catherine Godson, Alexander P. Maxwell, Amy Jayne McKnight
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
chronic kidney disease
diabetic kidney disease
genetic biomarkers
genetic risk score
UK Biobank
single nucleotide polymorphisms
Online Access:https://www.mdpi.com/1422-0067/24/13/11209

Internet

https://www.mdpi.com/1422-0067/24/13/11209

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