Generation of pulsatile ERK activity in mouse embryonic stem cells is regulated by Raf activity

Abstract The extracellular signal-regulated kinase (ERK) is a serine/threonine kinase that is known to regulate cellular events such as cell proliferation and differentiation. The ERK signaling pathway is activated by fibroblast growth factors, and is considered to be indispensable for the different...

Full description

Bibliographic Details
Main Authors: Yayoi Toyooka, Kazuhiro Aoki, Fumiko Matsukawa Usami, Sanae Oka, Azusa Kato, Toshihiko Fujimori
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36424-6