Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

Several studies have shown that RNAi-mediated depletion of splicing factors (SFs) results in mitotic abnormalities. However, it is currently unclear whether these abnormalities reflect defective splicing of specific pre-mRNAs or a direct role of the SFs in mitosis. Here, we show that two highly cons...

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Bibliographic Details
Main Authors: Claudia Pellacani, Elisabetta Bucciarelli, Fioranna Renda, Daniel Hayward, Antonella Palena, Jack Chen, Silvia Bonaccorsi, James G Wakefield, Maurizio Gatti, Maria Patrizia Somma
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
Sf3A2
Prp31
Ndc80
mitosis
Drosophila
HeLa cells
Online Access:https://elifesciences.org/articles/40325

Internet

https://elifesciences.org/articles/40325

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