Ubiquitin receptor binding and signaling in primary human leukocytes

Utilizing the human monocyte/macrophage cell line THP1, we recently identified extracellular ubiquitin as an endogenous agonist of the G protein-coupled receptor CXC chemokine receptor (CXCR) 4. Because receptor binding and signaling properties of extracellular ubiquitin have not been evaluated in p...

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Bibliographic Details
Main Authors: Vikas Saini, Jacqueline Romero, Adriano Marchese, Matthias Majetschak
Format: Article
Language:English
Published: Taylor & Francis Group 2010-11-01
Series:Communicative & Integrative Biology
Online Access:https://www.tandfonline.com/doi/10.4161/cib.3.6.13375