The role of E3 ubiquitin ligases in bone homeostasis and related diseases

The role of E3 ubiquitin ligases in bone homeostasis and related diseases

The ubiquitin–proteasome system (UPS) dedicates to degrade intracellular proteins to modulate demic homeostasis and functions of organisms. These enzymatic cascades mark and modifies target proteins diversly through covalently binding ubiquitin molecules. In the UPS, E3 ubiquitin ligases are the cru...

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Bibliographic Details
Main Authors: Yuechao Dong, Yangshan Chen, Guixing Ma, Huiling Cao
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
E3 ubiquitin ligase
UPS
Osteogenesis
Bone resorption
Osteoblast
Osteoclast
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523002496

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http://www.sciencedirect.com/science/article/pii/S2211383523002496

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