Comprehensive Assessment of Coronary Plaque Progression With Advanced Intravascular Imaging, Physiological Measures, and Wall Shear Stress: A Pilot Double‐Blinded Randomized Controlled Clinical Trial of Nebivolol Versus Atenolol in Nonobstructive Coronary Artery Disease

Comprehensive Assessment of Coronary Plaque Progression With Advanced Intravascular Imaging, Physiological Measures, and Wall Shear Stress: A Pilot Double‐Blinded Randomized Controlled Clinical Trial of Nebivolol Versus Atenolol in Nonobstructive Coronary Artery Disease

BackgroundWe hypothesized that nebivolol, a β‐blocker with nitric oxide–mediated activity, compared with atenolol, a β‐blocker without such activity, would decrease oxidative stress and improve the effects of endothelial dysfunction and wall shear stress (WSS), thereby reducing atherosclerosis progr...

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Bibliographic Details
Main Authors: Olivia Y. Hung, David Molony, Michel T. Corban, Emad Rasoul‐Arzrumly, Charles Maynard, Parham Eshtehardi, Saurabh Dhawan, Lucas H. Timmins, Marina Piccinelli, Sung Gyun Ahn, Bill D. Gogas, Michael C. McDaniel, Arshed A. Quyyumi, Don P. Giddens, Habib Samady
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
coronary flow
coronary microvascular function
endothelial function
intravascular ultrasound
wall shear stress
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.002764

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.002764

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