Differences in the organization of interface residues tunes the stability of the SARS-CoV-2 spike-ACE2 complex

Differences in the organization of interface residues tunes the stability of the SARS-CoV-2 spike-ACE2 complex

The continuous emergence of novel variants represents one of the major problems in dealing with the SARS-CoV-2 virus. Indeed, also due to its prolonged circulation, more than ten variants of concern emerged, each time rapidly overgrowing the current viral version due to improved spreading features....

Full description

Bibliographic Details
Main Authors: Mattia Miotto, Lorenzo Di Rienzo, Greta Grassmann, Fausta Desantis, Gianluca Cidonio, Giorgio Gosti, Marco Leonetti, Giancarlo Ruocco, Edoardo Milanetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
SARS-C0V-2
complex stability
Zernike 2D
SARS-COV-2 variants
energetic interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1205919/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1205919/full

Similar Items