“Tranq-dope” overdose and mortality: lethality induced by fentanyl and xylazine

“Tranq-dope” overdose and mortality: lethality induced by fentanyl and xylazine

Introduction: The recreational use of fentanyl in combination with xylazine (i.e., “tranq-dope”) represents a rapidly emerging public health threat characterized by significant toxicity and mortality. This study quantified the interactions between these drugs on lethality and examined the effectiven...

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Bibliographic Details
Main Authors: Mark A. Smith, Samantha L. Biancorosso, Jacob D. Camp, Salome H. Hailu, Alexandra N. Johansen, Mackenzie H. Morris, Hannah N. Carlson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
addiction
isobologram
opioid use disorder
preclinical model
sex differences
substance use
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1280289/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1280289/full

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