Glioblastoma disrupts the ependymal wall and extracellular matrix structures of the subventricular zone

Glioblastoma disrupts the ependymal wall and extracellular matrix structures of the subventricular zone

Abstract Background Glioblastoma (GBM) is the most aggressive and common type of primary brain tumor in adults. Tumor location plays a role in patient prognosis, with tumors proximal to the lateral ventricles (LVs) presenting with worse overall survival, increased expression of stem cell genes, and...

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Bibliographic Details
Main Authors: Emily S. Norton, Lauren A. Whaley, María José Ulloa-Navas, Patricia García-Tárraga, Kayleah M. Meneses, Montserrat Lara-Velazquez, Natanael Zarco, Anna Carrano, Alfredo Quiñones-Hinojosa, José Manuel García-Verdugo, Hugo Guerrero-Cázares
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Lateral ventricle
Stem cell niche
Subependymal zone
Glioma
Cerebrospinal fluid (CSF)
Lipid droplets
Online Access:https://doi.org/10.1186/s12987-022-00354-8

Internet

https://doi.org/10.1186/s12987-022-00354-8

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