Peptide foldamer-based inhibitors of the SARS-CoV-2 S protein–human ACE2 interaction

Peptide foldamer-based inhibitors of the SARS-CoV-2 S protein–human ACE2 interaction

The entry of the SARS-CoV-2 virus into a human host cell begins with the interaction between the viral spike protein (S protein) and human angiotensin-converting enzyme 2 (hACE2). Therefore, a possible strategy for the treatment of this infection is based on inhibiting the interaction of the two abo...

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Bibliographic Details
Main Authors: Violeta Marković, Jeelan Basha Shaik, Katarzyna Ożga, Agnieszka Ciesiołkiewicz, Juan Lizandra Perez, Ewa Rudzińska-Szostak, Łukasz Berlicki
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
COVID-19
foldamers
peptides
helix
protein-protein interaction
BLI
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2023.2244693

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2023.2244693

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