The Appalachia Mind Health Initiative (AMHI): a pragmatic randomized clinical trial of adjunctive internet-based cognitive behavior therapy for treating major depressive disorder among primary care patients

The Appalachia Mind Health Initiative (AMHI): a pragmatic randomized clinical trial of adjunctive internet-based cognitive behavior therapy for treating major depressive disorder among primary care patients

Abstract Background Major depressive disorder (MDD) is a leading cause of disease morbidity. Combined treatment with antidepressant medication (ADM) plus psychotherapy yields a much higher MDD remission rate than ADM only. But 77% of US MDD patients are nonetheless treated with ADM only despite stro...

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Bibliographic Details
Main Authors: Robert M. Bossarte, Ronald C. Kessler, Andrew A. Nierenberg, Ambarish Chattopadhyay, Pim Cuijpers, Angel Enrique, Phyllis M. Foxworth, Sarah M. Gildea, Bea Herbeck Belnap, Marc W. Haut, Kari B. Law, William D. Lewis, Howard Liu, Alexander R. Luedtke, Wilfred R. Pigeon, Larry A. Rhodes, Derek Richards, Bruce L. Rollman, Nancy A. Sampson, Cara M. Stokes, John Torous, Tyler D. Webb, Jose R. Zubizarreta
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Trials
Subjects:
Appalachian Mind Health Initiative (AMHI)
Major depressive disorder
i-CBT
Remission from depression
Antidepressant medication
Heterogeneity of treatment effects
Online Access:https://doi.org/10.1186/s13063-022-06438-y

Internet

https://doi.org/10.1186/s13063-022-06438-y

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