Identification of potential targets of the curcumin analog CCA-1.1 for glioblastoma treatment : integrated computational analysis and in vitro study

Abstract The treatment of glioblastoma multiforme (GBM) is challenging owing to its localization in the brain, the limited capacity of brain cells to repair, resistance to conventional therapy, and its aggressiveness. Curcumin has anticancer activity against aggressive cancers, such as leukemia, and...

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Bibliographic Details
Main Authors: Adam Hermawan, Febri Wulandari, Naufa Hanif, Rohmad Yudi Utomo, Riris Istighfari Jenie, Muthi Ikawati, Ahmad Syauqy Tafrihani
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18348-9