The future of retinal gene therapy: evolving from subretinal to intravitreal vector delivery

The future of retinal gene therapy: evolving from subretinal to intravitreal vector delivery

Inherited retinal degenerations are a leading and untreatbale cause of blindness, and as such they are targets for gene therapy. Numerous gene therapy treatments have progressed from laboratory research to clinical trails, and a pioneering gene therapy received the first ever FDA approval for treati...

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Bibliographic Details
Main Authors: Maya Ross, Ron Ofri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
adeno-associated virus; animal model; blindness; gene therapy; inner limiting membrane; photoreceptors; retina; retinitis pigmentosa; vitreous
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=9;spage=1751;epage=1759;aulast=Ross

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=9;spage=1751;epage=1759;aulast=Ross

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