Longitudinal Circulating Tumor DNA Profiling in Metastatic Colorectal Cancer During Anti-EGFR Therapy

Longitudinal Circulating Tumor DNA Profiling in Metastatic Colorectal Cancer During Anti-EGFR Therapy

BackgroundMetastatic colorectal cancer (mCRC) is a heterogenous disease with limited precision medicine and targeted therapy options. Monoclonal antibodies against epidermal growth factor receptor (EGFR) have been a crucial treatment option for mCRC. However, proper biomarkers for predicting therape...

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Bibliographic Details
Main Authors: Wentao Yang, Jianling Zou, Ye Li, Rujiao Liu, Zhengqing Yan, Shiqing Chen, Xiaoying Zhao, Weijian Guo, Mingzhu Huang, Wenhua Li, Xiaodong Zhu, Zhiyu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
next-generation sequencing
circulating tumor DNA
dynamic monitoring
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.830816/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.830816/full

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