AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1
ABSTRACT Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon reactivation of the virus in immunocompromised patients, may trigger an innate immune response and induce damag...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-10-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.00417-23 |