Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants and are associated with human disease. Canonically, many PAHs induce toxicity via activation of the aryl hydrocarbon receptor (AHR) pathway. While the interaction between PAHs and the AHR is well-established, understan...

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Bibliographic Details
Main Authors: Lindsay B. Wilson, Ryan S. McClure, Katrina M. Waters, Michael T. Simonich, Robyn L. Tanguay
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Toxicology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2022.950503/full