Predictors of HVTN 503 MRK-AD5 HIV-1 gag/pol/nef vaccine induced immune responses.

Predictors of HVTN 503 MRK-AD5 HIV-1 gag/pol/nef vaccine induced immune responses.

Phambili, the Merck (MRK)-Adenovirus Type 5 (Ad5) HIV-1 gag/pol/nef subtype B vaccine study, conducted in South Africa, suspended enrollment and vaccination when companion study, Step, was found non-efficacious. Although the vaccine did not prevent HIV-1 infection or lower viral-load setpoint, immun...

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Bibliographic Details
Main Authors: Kathryn L Hopkins, Fatima Laher, Kennedy Otwombe, Gavin Churchyard, Linda-Gail Bekker, Stephen DeRosa, Maphoshane Nchabeleng, Koleka Mlisana, James Kublin, Glenda Gray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4121165?pdf=render

Internet

http://europepmc.org/articles/PMC4121165?pdf=render

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