Transmembrane domain quality control systems operate at the endoplasmic reticulum and Golgi apparatus.

Multiple protein quality control systems operate to ensure that misfolded proteins are efficiently cleared from the cell. While quality control systems that assess the folding status of soluble domains have been extensively studied, transmembrane domain (TMD) quality control mechanisms are poorly un...

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Bibliographic Details
Main Authors: Kit Briant, Nicholas Johnson, Eileithyia Swanton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5383021?pdf=render