Renal erythropoietin-producing cells in health and disease

Renal erythropoietin-producing cells in health and disease

Erythropoietin (Epo) is an indispensable erythropoietic hormone primarily produced from renal Epo-producing cells (REPs). Epo production in REPs is tightly regulated in a hypoxia-inducible manner to maintain tissue oxygen homeostasis. Insufficient Epo production by REPs causes renal anemia and anemi...

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Bibliographic Details
Main Authors: Tomokazu eSouma, Norio eSuzuki, Masayuki eYamamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Physiology
Subjects:
Erythropoietin
Fibrosis
plasticity
hypoxia
Renal Epo-producing cell (REP)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00167/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00167/full

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