Real-time imaging of human endothelial-to-hematopoietic transition in vitro using pluripotent stem cell derived hemogenic endothelium

Real-time imaging of human endothelial-to-hematopoietic transition in vitro using pluripotent stem cell derived hemogenic endothelium

During embryogenesis, human hematopoietic stem cells (HSCs) first emerge in the aorta-gonad-mesonephros (AGM) region via transformation of specialized hemogenic endothelial (HE) cells into premature HSC precursors. This process is termed endothelial-to-hematopoietic transition (EHT), in which the HE...

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Bibliographic Details
Main Authors: Yuriko Yoneda, Hisaya Kato, Yoshiro Maezawa, Koutaro Yokote, Mio Nakanishi
Format: Article
Language:English
Published: The Biophysical Society of Japan 2024-05-01
Series:Biophysics and Physicobiology
Subjects:
hematopoietic stem and progenitor cell
aorta-gonad-mesonephros region
live cell imaging
Online Access:https://doi.org/10.2142/biophysico.bppb-v21.s015

Internet

https://doi.org/10.2142/biophysico.bppb-v21.s015

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