The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice

The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice

Our aim was to determine whether polyphosphazene (PCEP), Curdlan (β-glucan, a dectin-1 agonist), and Leptin could act as adjuvants to promote a Th17-type adaptive immune response in mice. Mice were vaccinated via the intramuscular route then boosted three weeks later with Ovalbumin plus: PCEP, Lepti...

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Bibliographic Details
Main Authors: Alyssa Chaffey, Glenn Hamonic, Dylan Chand, George K. Mutwiri, Heather L. Wilson
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Vaccines
Subjects:
mice
ovalbumin
cell-mediated immunity
flow cytometry
interleukin-17
Th17-type T cells
Online Access:https://www.mdpi.com/2076-393X/9/5/507

Internet

https://www.mdpi.com/2076-393X/9/5/507

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